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Yujiao Mu, Ruichao Li, Pengcheng Du, Pei Zhang, Yan Li, Shenghui Cui, Séamus Fanning, Li Bai
Engineering 2022, Volume 15, Issue 8, Pages 34-44 doi: 10.1016/j.eng.2022.05.006
Salmonella enterica serovar 4,[5],12:i:- (S. 4,[5],12:i:-) is a monophasic variant of Salmonella enterica serovar Typhimurium that has emergedresistance (AMR) phenotypes, and population genomics of sequence type 34 (ST34) S. 4,[5],12:i:A total of 100 ST34 S. 4,[5],12:i:- isolates were studied from 2008 to 2017 and found mostlyand tet(B) (TET) inserted into the fljBA operon, was responsible for most of the monophasic
Keywords: <i>Salmonella Typhimuriumi> monophasic variant ST34 Prevalence Phylogenetic analysis Chinese lineages
Frontiers of Medicine 2023, Volume 17, Issue 3, Pages 493-502 doi: 10.1007/s11684-022-0946-x
Keywords: <i>ALKi> fusion next-generation sequencing fluorescence <i>in situi> hybridization immunohistochemistry variant allele frequency intratumoral heterogeneity targeted therapy
A novel variant in the gene in a large Chinese family with a unique phenotype of Clouston syndrome
Frontiers of Medicine 2023, Volume 17, Issue 2, Pages 330-338 doi: 10.1007/s11684-022-0933-2
Keywords: Clouston syndrome whole exome sequencing <i>GJB6i> gene novel variant unique phenotype
Novel variants in LAMA3 and COL7A1 and recurrent variant in KRT5 underlying epidermolysis bullosa in
Frontiers of Medicine 2022, Volume 16, Issue 5, Pages 808-814 doi: 10.1007/s11684-021-0878-x
Keywords: epidermolysis bullosa <i>LAMA3i> <i>COL7A1i> <i>KRT5i> Chinese families
Ram Prasad Aganja, Amal Senevirathne, Chandran Sivasankar, John Hwa Lee
Engineering 2024, Volume 32, Issue 1, Pages 42-57 doi: 10.1016/j.eng.2023.08.001
Keywords: COBRA Influenza A <i>Salmonellai> Vaccine Broad spectral protection
Frontiers of Medicine 2022, Volume 16, Issue 6, Pages 873-882 doi: 10.1007/s11684-022-0925-2
Keywords: <i>Salmonellai> VNP20009 tumstatin B16F10 melanoma apoptosis angiogenesis
Effectiveness of inactivated COVID-19 vaccine against the severity of Omicron variant
Frontiers of Medicine 2023, Volume 17, Issue 3, Pages 576-580 doi: 10.1007/s11684-023-0991-0
Keywords: variant
Yuting Shang,Shuzhen Cai,Qinghua Ye,Qingping Wu,Yanna Shao,Xiaoying Qu,Xinran Xiang,Baoqing Zhou,Yu Ding,Moutong Chen,Liang Xue,Honghui Zhu,Jumei Zhang
Engineering 2022, Volume 19, Issue 12, Pages 62-70 doi: 10.1016/j.eng.2021.03.024
Keywords: Salmonella Typhimurium Quantum dot nanobeads Lateral flow immunoassay strip Loop-mediated isothermal
Dong Wang, Min Tian, Guanglin Cui, Dao Wen Wang
Frontiers of Medicine 2018, Volume 12, Issue 3, Pages 319-323 doi: 10.1007/s11684-017-0553-4
Keywords: antithrombin deficiency protein C activity mutation variant venous thromboembolism anticoagulants
Exergy and exergoeconomic analyses for integration of aromatics separation with aromatics upgrading
Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 2, Pages 183-193 doi: 10.1007/s11705-022-2192-9
Keywords: aromatics separation and upgrading variant splitting ratios total exergy destruction total product
Yuzhou WANG,Tongyan WANG,He YAN,Fanli YANG,Linghua GUO,Qingyuan YANG,Xule HU,Feifei TAN,Yan XIAO,Xiangdong LI,Kegong TIAN
Frontiers of Agricultural Science and Engineering 2015, Volume 2, Issue 3, Pages 216-222 doi: 10.15302/J-FASE-2015072
Keywords: pseudorabies virus glycoprotein B protein subunit vaccine
Genome-wide association studies: inherent limitations and future challenges
Yan Du, Jiaxin Xie, Wenjun Chang, Yifang Han, Guangwen Cao
Frontiers of Medicine 2012, Volume 6, Issue 4, Pages 444-450 doi: 10.1007/s11684-012-0225-3
Genome-wide association studies (GWAS) have achieved great success in identifying genetic variants related to complex human diseases such as cancer and have provided valuable insights into their genetic architecture. Recently, GWAS is quite the fashion in China. However, there are issues related to its nature. Enormous work needs to be done in the post-GWAS era. Deep sequencing followed by functional studies will be needed to elucidate the underpinning biological mechanisms and further translate GWAS findings into medical practice. Along with pharmacogenomics, the success of GWAS in identifying genetic risk factors and genetic differences in drug response has been gradually enabling personalized medicine. In this article, we used hepatocellular carcinoma (HCC) as an example to demonstrate some of the inherent limitations and summarized future challenges of GWAS.
Keywords: genome-wide association studies (GWAS) genetic variant cancer limitation challenge
Asghar RAHMATI,Lohrasb FARAMARZI,Manouchehr SANEI
Frontiers of Structural and Civil Engineering 2014, Volume 8, Issue 4, Pages 448-455 doi: 10.1007/s11709-014-0262-x
Keywords: <i>JHi> classification <i>Qi> and <i>RMRi> classification new method
Shengwen Tang,Yuting Hu,Shengfu Zhong,Peigao Luo
Engineering 2018, Volume 4, Issue 4, Pages 500-506 doi: 10.1016/j.eng.2018.06.004
Powdery mildew, which is caused by Blumeria graminis f. sp. tritici (Bgt), is an important leaf disease that affects wheat yield. Powdery mildew-resistance (Pm) gene Pm21 was first transferred into wheat in the 1980s, by translocating the Heuchera villosa chromosome arm 6VS to the wheat chromosome arm 6AL (6VS·6AL). Recently, new Bgt isolates that are virulent to Pm21 have been identified in some wheat fields, indicating that wheat breeders should be aware of the risk of deploying Pm21, although pathological details regarding these virulent isolates still remain to be discovered. Pm40 was identified and mapped on the wheat chromosome arm 7BS from several wheat lines developed from the progenies of a wild cross between wheat and Thinopyrum intermedium. Pm40 offers a broad spectrum of resistance to Bgt, which suggests that it is likely to provide potentially durable resistance. Cytological methods did not detect any large alien chromosomal segment in the wheat lines carrying Pm40. Lines with Pm40 and promising agronomical traits have been released by several wheat-breeding programs in the past several years. Therefore, we believe that Pm40 will play a role in powdery mildew-resistance wheat breeding after Pm21 resistance is overcome by Bgt isolates. In addition, both Pm21 and Pm40 were derived from alien species, suggesting that the resistance genes derived from alien species are potentially more durable or effective than those identified from wheat.
Keywords: Wheat Powdery mildew <i>Pm21i> <i>Pm40i> Alien species Native resistance
NiFeRuO<i>xi> nanosheets on Ni foam as an electrocatalyst for efficient
Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 11, Pages 1698-1706 doi: 10.1007/s11705-023-2334-8
Keywords: NiFeRuO<i>xi> nanosheets Ni foam electrocatalysis overall seawater splitting solar-driven
Title Author Date Type Operation
Genomic Epidemiology of ST34 Monophasic Salmonella enterica Serovar Typhimurium from Clinical Patients
Yujiao Mu, Ruichao Li, Pengcheng Du, Pei Zhang, Yan Li, Shenghui Cui, Séamus Fanning, Li Bai
Journal Article
Potential unreliability of ALK variant allele frequency in the efficacy prediction of targeted therapy
Journal Article
A novel variant in the gene in a large Chinese family with a unique phenotype of Clouston syndrome
Journal Article
Novel variants in LAMA3 and COL7A1 and recurrent variant in KRT5 underlying epidermolysis bullosa in
Journal Article
<i>Salmonellai>-Delivered COBRA-HA1 Antigen Derived from H1N1 Hemagglutinin Sequences Elicits Broad-Spectrum
Ram Prasad Aganja, Amal Senevirathne, Chandran Sivasankar, John Hwa Lee
Journal Article
Bacteria-mediated tumor-targeted delivery of tumstatin (54-132) significantly suppresses tumor growth in mouse model by inhibiting angiogenesis and promoting apoptosis
Journal Article
Effectiveness of inactivated COVID-19 vaccine against the severity of Omicron variant
Journal Article
Quantum Dot Nanobeads-Labelled Lateral Flow Immunoassay Strip for Rapid and Sensitive Detection of <i>Salmonellai> Typhimurium Based on Strand Displacement Loop-Mediated Isothermal Amplification
Yuting Shang,Shuzhen Cai,Qinghua Ye,Qingping Wu,Yanna Shao,Xiaoying Qu,Xinran Xiang,Baoqing Zhou,Yu Ding,Moutong Chen,Liang Xue,Honghui Zhu,Jumei Zhang
Journal Article
Antithrombin deficiency and decreased protein C activity in a young man with venous thromboembolism: a case report
Dong Wang, Min Tian, Guanglin Cui, Dao Wen Wang
Journal Article
Exergy and exergoeconomic analyses for integration of aromatics separation with aromatics upgrading
Journal Article
Research and development of a novel subunit vaccine for the currently circulating pseudorabies virus variant
Yuzhou WANG,Tongyan WANG,He YAN,Fanli YANG,Linghua GUO,Qingyuan YANG,Xule HU,Feifei TAN,Yan XIAO,Xiangdong LI,Kegong TIAN
Journal Article
Genome-wide association studies: inherent limitations and future challenges
Yan Du, Jiaxin Xie, Wenjun Chang, Yifang Han, Guangwen Cao
Journal Article
Development of a new method for RMR and Q classification method to optimize support system in tunneling
Asghar RAHMATI,Lohrasb FARAMARZI,Manouchehr SANEI
Journal Article
The Potential Role of Powdery Mildew-Resistance Gene <i>Pm40i> in Chinese Wheat-Breeding Programs inthe Post-<i>Pm21i> Era
Shengwen Tang,Yuting Hu,Shengfu Zhong,Peigao Luo
Journal Article